A comparative study on photobiological effects of low-level laser therapy and tinnitus retraining therapy in patients with acoustic trauma-induced tinnitus
,
Abstract
Background and Aim: Tinnitus is a subjective auditory symptom referred to the perception of sound in the absence of external stimuli, and there is no definite treatment for it. Rehabilitation methods and laser therapy have been recommended used for its management. This study aimed to investigate the photobiological effects of low-level laser therapy (LLLT) and tinnitus retraining therapy (TRT) in patients with acoustic trauma-induced tinnitus.
Methods: This clinical trial was conducted on 60 patients suffering from acoustic trauma-induced tinnitus for more than six months, divided into three groups of LLLT, TRT and LLLT + TRT. The Persian version of tinnitus handicap inventory (P-THI), visual analog scale (VAS), and loudness match (LM) scale were used to collect data. The collected data were analyzed in SPSS version.22 software. The effect of time, group and time × group on the scores of VAS, LM, P-THI and its subscales were examined.
Results: There was a statistically significant difference between LLLT + TRT and LLLT groups after intervention in terms of LM (p = 0.002) and VAS (p = 0.001) variables, but no statistical significance for P-THI and its subscales (p = 0.442) was found.
Conclusion: Combination of LLLT and TRT, as a therapeutic protocol, is recommended due to their remarkable effects in reducing acoustic trauma-induced tinnitus symptoms. The use of LLLT method alone, however, is not recommended due to its lower effects.
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2. Tyler RS, Noble W, Coelho C, Roncancio ER, Jun HJ. Tinnitus and hyperacusis. In: Katz J, Chasin M, Hood LJ, Tillery KL, editors. Handbook of clinical audiology. 7th ed. Philadelphia: Wolters Kluwer Helth; 2015. p. 647-58.
3. Lockwood AH, Salvi RJ, Burkard RF. Tinnitus. N Engl J Med. 2002;347(12):904-10. doi: 10.1056/NEJMra013395
4. Nondahl DM, Cruickshanks KJ, Wiley TL, Klein R, Klein BEK, Tweed TS. Prevalence and 5-year incidence of tinnitus among older adults: the epidemiology of hearing loss study. J Am Acad Audiol. 2002;13(6):323-31. doi: 10.1055/s-0040-1715975
5. Folmer RL, McMillan GP, Austin DF, Henry JA. Audio¬metric thresholds and prevalence of tinnitus among male veterans in the United States: data from the National Health and Nutrition Examination Survey, 1999-2006. J Rehabil Res Dev. 2011;48(5):503-16. doi: 10.1682/jrrd.2010.07.0138
6. MacGregor AJ, Joseph AR, Dougherty AL. Prevalence of tinnitus and association with self-rated health among military personnel injured on combat deployment. Mil Med. 2020;185(9-10):e1608-14. doi: 10.1093/milmed/usaa103
7. Chang SY, Lim SK, young Lee M, Chung PS, Jung JY, Rhee CK. Combination therapy using antioxidants and low level laser therapy (LLLT) on noise induced hearing loss (NIHL). Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII; February 29, 2016: San Francisco, United States. doi: 10.1117/12.2212380
8. Simpson JJ, Davies WE. Recent advances in the pharmacological treatment of tinnitus. Trends Pharmacol Sci. 1999;20(1):12-8. doi: 10.1016/s0165-6147(98)01281-4
9. Tunér J, Hode L. Low level laser therapy. Graengesberg: Prima Books in Sweden AB; 1999.
10. Ogawa K, Sato H, Takahashi M, Wada T, Naito Y, Kawase T, et al. Clinical practice guidelines for diagnosis and treatment of chronic tinnitus in Japan. Auris Nasus Larynx. 2020;47(1):1-6. doi: 10.1016/j.anl.2019.09.007
11. Lee K, Makino K, Yamahara K. Evaluation of tinnitus retraining therapy for patients with normal audiograms versus patients with hearing loss. Auris Nasus Larynx. 2018;45(2):215-21. doi: 10.1016/j.anl.2017.03.009
12. Teggi R, Bellini C, Fabiano B, Bussi M. Efficacy of low-level laser therapy in Ménière's disease: a pilot study of 10 patients. Photomed Laser Surg. 2008;26(4):349-53. doi: 10.1089/pho.2007.2186
13. Chen CH, Huang CY, Chang CY, Cheng YF. Efficacy of low-level laser therapy for tinnitus: A systematic review with meta-analysis and trial sequential analysis. Brain Sci. 2020;10(12):931. doi: 10.3390/brainsci10120931
14. Farivar S, Malekshahabi T, Shiari R. Biological effects of low level laser therapy. J Lasers Med Sci. 2014;5(2):58-62.
15. Prochazka M, Tejnska R. Noninvasive laser in therapy of tinnitus. Proc. SPIE 4166, Laser Florence'99: A Window on the Laser Medicine World; June 28, 2000: Florence, Italy. doi: 10.1117/12.389489
16. Tinnitus Retraining Therapy Trial Research Group, Scherer RW, Formby C. Effect of tinnitus retraining therapy vs standard of care on tinnitus-related quality of life: a randomized clinical trial. JAMA Otolaryngol Head Neck Surg. 2019;145(7):597-608. doi: 10.1001/jamaoto.2019.0821
17. Nemade SV, Shinde KJ. Clinical efficacy of tinnitus retraining therapy based on tinnitus questionnaire score and visual analogue scale score in patients with subjective tinnitus. Turk Arch Otorhinolaryngol. 2019;57(1):34-8. doi: 10.5152/tao.2019.3091
18. Fitzpatrick RE. Lasers in dermatology & plastic surgery. Optics and Photonics News. 1995;6(11):23-31.
19. Mahmoudian S, Shahmiri E, Rouzbahani M, Jafari Z, Keyhani MR, Rahimi F, et al. Persian language version of the “Tinnitus Handicap Inventory”: translation, standardization, validity and reliability. Int Tinnitus J. 2011;16(2):93-103.
20. Newman CW, Jacobson GP, Spitzer JB. Development of the tinnitus handicap inventory. Arch Otolaryngol Head Neck Surg. 1996;122(2):143-8. doi: 10.1001/archotol.1996.01890140029007
21. Salahaldin AH, Abdulhadi K, Najjar N, Bener A. Low-level laser therapy in patients with complaints of tinnitus: a clinical study. International Scholarly Research Notices. 2012;2012.
22. Jastreboff P. Tinnitus retraining therapy. In: Møller AR, Langguth B, Ridder D, Kleinjung T, editors. Textbook of tinnitus. New York: Springer; 2011. p. 575-96.
23. Jastreboff PJ, Jastreboff MM. Tinnitus retraining therapy (TRT) as a method for treatment of tinnitus and hyperacusis patients. J Am Acad Audiol. 2000;11(3):162-77.
24. Moossavi A, Sadeghijam M, Akbari M. The hypothetical relation between the degree of stress and auditory cortical evoked potentials in tinnitus sufferers. Med Hypotheses. 2019;130:109266. doi: 10.1016/j.mehy.2019.109266
25. Prakash SGR, Aparna R, Kumar SB, Madhav T, Ashritha K, Navyatha K. Sensori-Neural Hearing Loss Client’s performance with receiver-in-canal (RIC) hearing aids. International Journal of Otolaryn¬gology and Head & Neck Surgery. 2013;2(2): doi: 10.4236/ijohns.2013.22017
26. Shiomi Y, Takahashi H, Honjo I, Kojima H, Naito Y, Fujiki N. Efficacy of transmeatal low power laser irradiation on tinnitus: a preliminary report. Auris Nasus Larynx. 1997;24(1):39-42. doi: 10.1016/S0385-8146(96)00003-X
27. Demirkol N, Usumez A, Demirkol M, Sari F, Akcaboy C. Efficacy of low-level laser therapy in subjective tinnitus patients with temporomandibular disorders. Photomed Laser Surg. 2017;35(8):427-31. doi: 10.1089/pho.2016.4240
28. Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M. Alterations in auditory electrophysiological responses associated with temporary suppression of tinnitus induced by low-level laser therapy: a before-after case series. J Lasers Med Sci. 2017;8(Suppl 1):S38-45. doi: 10.15171/jlms.2017.s8
29. Gungor A, Dogru S, Cincik H, Erkul E, Poyrazoglu E. Effectiveness of transmeatal low power laser irradiation for chronic tinnitus. J Laryngol Otol. 2008;122(5):447-51. doi: 10.1017/S0022215107009619
30. Oron U, Ilic S, De Taboada L, Streeter J. Ga-As (808 nm) laser irradiation enhances ATP production in human neuronal cells in culture. Photomed Laser Surg. 2007;25(3):180-2. doi: 10.1089/pho.2007.2064
31. Hitz CB, Ewing JJ, Hecht J. Introduction to laser technology. 4th ed. Hoboken, NJ: John Wiley & Sons; 2012.
32. Ashmore J. Cochlear outer hair cell motility. Physiol Rev. 2008;88(1):173-210. doi: 10.1152/physrev.00044.2006
33. Jastreboff PJ, Jastreboff MM. Tinnitus retraining therapy: a different view on tinnitus. ORL J Otorhinolaryngol Relat Spec. 2006;68(1):23-30.
34. Davis PB, James LS, Mcsweeney BA, Laidlaw LE, Frater RH, Hanley PJ. Inventors; Neuromonics Pty Ltd, assignee. Tinnitus rehabilitation device and method. United States patent US 7,520,851. 2009 Apr 21.
35. Ricketts TA, Picou EM, Shehorn J, Dittberner AB. Degree of hearing loss affects bilateral hearing aid benefits in ecologically relevant laboratory conditions. J Speech Lang Hear Res. 2019;62(10):3834-50. doi: 10.1044/2019_JSLHR-H-19-0013
36. Shekhawat GS, Searchfield GD, Stinear CM. Role of hearing aids in tinnitus intervention: a scoping review. J Am Acad Audiol. 2013;24(8):747-62. doi: 10.3766/jaaa.24.8.11
37. Sereda M, McFerran D, Axon E, Baguley DM, Hall DA, Potgieter I, et al. A process for prioritising systematic reviews in tinnitus. Int J Audiol. 2020;59(8):640-6. doi: 10.1080/14992027.2020.1733677
38. Brueggemann P, Szczepek AJ, Seydel C, Schaefer C, Szczepek A, Amarjargal N, et al. ICD-10 symptom rating questionnaire for assessment of psychological comorbidities in patients with chronic tinnitus. HNO. 2019;67(3):178-83. doi: 10.1007/s00106-019-0618-6
39. Kumar Reddy KV, Chaitanya VK, Babu GR. Efficacy of tinnitus retraining therapy, a modish management of tinnitus: our experience. Indian J Otolaryngol Head Neck Surg. 2019;71(1):95-8. doi: 10.1007/s12070-018-1392-6
2. Tyler RS, Noble W, Coelho C, Roncancio ER, Jun HJ. Tinnitus and hyperacusis. In: Katz J, Chasin M, Hood LJ, Tillery KL, editors. Handbook of clinical audiology. 7th ed. Philadelphia: Wolters Kluwer Helth; 2015. p. 647-58.
3. Lockwood AH, Salvi RJ, Burkard RF. Tinnitus. N Engl J Med. 2002;347(12):904-10. doi: 10.1056/NEJMra013395
4. Nondahl DM, Cruickshanks KJ, Wiley TL, Klein R, Klein BEK, Tweed TS. Prevalence and 5-year incidence of tinnitus among older adults: the epidemiology of hearing loss study. J Am Acad Audiol. 2002;13(6):323-31. doi: 10.1055/s-0040-1715975
5. Folmer RL, McMillan GP, Austin DF, Henry JA. Audio¬metric thresholds and prevalence of tinnitus among male veterans in the United States: data from the National Health and Nutrition Examination Survey, 1999-2006. J Rehabil Res Dev. 2011;48(5):503-16. doi: 10.1682/jrrd.2010.07.0138
6. MacGregor AJ, Joseph AR, Dougherty AL. Prevalence of tinnitus and association with self-rated health among military personnel injured on combat deployment. Mil Med. 2020;185(9-10):e1608-14. doi: 10.1093/milmed/usaa103
7. Chang SY, Lim SK, young Lee M, Chung PS, Jung JY, Rhee CK. Combination therapy using antioxidants and low level laser therapy (LLLT) on noise induced hearing loss (NIHL). Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII; February 29, 2016: San Francisco, United States. doi: 10.1117/12.2212380
8. Simpson JJ, Davies WE. Recent advances in the pharmacological treatment of tinnitus. Trends Pharmacol Sci. 1999;20(1):12-8. doi: 10.1016/s0165-6147(98)01281-4
9. Tunér J, Hode L. Low level laser therapy. Graengesberg: Prima Books in Sweden AB; 1999.
10. Ogawa K, Sato H, Takahashi M, Wada T, Naito Y, Kawase T, et al. Clinical practice guidelines for diagnosis and treatment of chronic tinnitus in Japan. Auris Nasus Larynx. 2020;47(1):1-6. doi: 10.1016/j.anl.2019.09.007
11. Lee K, Makino K, Yamahara K. Evaluation of tinnitus retraining therapy for patients with normal audiograms versus patients with hearing loss. Auris Nasus Larynx. 2018;45(2):215-21. doi: 10.1016/j.anl.2017.03.009
12. Teggi R, Bellini C, Fabiano B, Bussi M. Efficacy of low-level laser therapy in Ménière's disease: a pilot study of 10 patients. Photomed Laser Surg. 2008;26(4):349-53. doi: 10.1089/pho.2007.2186
13. Chen CH, Huang CY, Chang CY, Cheng YF. Efficacy of low-level laser therapy for tinnitus: A systematic review with meta-analysis and trial sequential analysis. Brain Sci. 2020;10(12):931. doi: 10.3390/brainsci10120931
14. Farivar S, Malekshahabi T, Shiari R. Biological effects of low level laser therapy. J Lasers Med Sci. 2014;5(2):58-62.
15. Prochazka M, Tejnska R. Noninvasive laser in therapy of tinnitus. Proc. SPIE 4166, Laser Florence'99: A Window on the Laser Medicine World; June 28, 2000: Florence, Italy. doi: 10.1117/12.389489
16. Tinnitus Retraining Therapy Trial Research Group, Scherer RW, Formby C. Effect of tinnitus retraining therapy vs standard of care on tinnitus-related quality of life: a randomized clinical trial. JAMA Otolaryngol Head Neck Surg. 2019;145(7):597-608. doi: 10.1001/jamaoto.2019.0821
17. Nemade SV, Shinde KJ. Clinical efficacy of tinnitus retraining therapy based on tinnitus questionnaire score and visual analogue scale score in patients with subjective tinnitus. Turk Arch Otorhinolaryngol. 2019;57(1):34-8. doi: 10.5152/tao.2019.3091
18. Fitzpatrick RE. Lasers in dermatology & plastic surgery. Optics and Photonics News. 1995;6(11):23-31.
19. Mahmoudian S, Shahmiri E, Rouzbahani M, Jafari Z, Keyhani MR, Rahimi F, et al. Persian language version of the “Tinnitus Handicap Inventory”: translation, standardization, validity and reliability. Int Tinnitus J. 2011;16(2):93-103.
20. Newman CW, Jacobson GP, Spitzer JB. Development of the tinnitus handicap inventory. Arch Otolaryngol Head Neck Surg. 1996;122(2):143-8. doi: 10.1001/archotol.1996.01890140029007
21. Salahaldin AH, Abdulhadi K, Najjar N, Bener A. Low-level laser therapy in patients with complaints of tinnitus: a clinical study. International Scholarly Research Notices. 2012;2012.
22. Jastreboff P. Tinnitus retraining therapy. In: Møller AR, Langguth B, Ridder D, Kleinjung T, editors. Textbook of tinnitus. New York: Springer; 2011. p. 575-96.
23. Jastreboff PJ, Jastreboff MM. Tinnitus retraining therapy (TRT) as a method for treatment of tinnitus and hyperacusis patients. J Am Acad Audiol. 2000;11(3):162-77.
24. Moossavi A, Sadeghijam M, Akbari M. The hypothetical relation between the degree of stress and auditory cortical evoked potentials in tinnitus sufferers. Med Hypotheses. 2019;130:109266. doi: 10.1016/j.mehy.2019.109266
25. Prakash SGR, Aparna R, Kumar SB, Madhav T, Ashritha K, Navyatha K. Sensori-Neural Hearing Loss Client’s performance with receiver-in-canal (RIC) hearing aids. International Journal of Otolaryn¬gology and Head & Neck Surgery. 2013;2(2): doi: 10.4236/ijohns.2013.22017
26. Shiomi Y, Takahashi H, Honjo I, Kojima H, Naito Y, Fujiki N. Efficacy of transmeatal low power laser irradiation on tinnitus: a preliminary report. Auris Nasus Larynx. 1997;24(1):39-42. doi: 10.1016/S0385-8146(96)00003-X
27. Demirkol N, Usumez A, Demirkol M, Sari F, Akcaboy C. Efficacy of low-level laser therapy in subjective tinnitus patients with temporomandibular disorders. Photomed Laser Surg. 2017;35(8):427-31. doi: 10.1089/pho.2016.4240
28. Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M. Alterations in auditory electrophysiological responses associated with temporary suppression of tinnitus induced by low-level laser therapy: a before-after case series. J Lasers Med Sci. 2017;8(Suppl 1):S38-45. doi: 10.15171/jlms.2017.s8
29. Gungor A, Dogru S, Cincik H, Erkul E, Poyrazoglu E. Effectiveness of transmeatal low power laser irradiation for chronic tinnitus. J Laryngol Otol. 2008;122(5):447-51. doi: 10.1017/S0022215107009619
30. Oron U, Ilic S, De Taboada L, Streeter J. Ga-As (808 nm) laser irradiation enhances ATP production in human neuronal cells in culture. Photomed Laser Surg. 2007;25(3):180-2. doi: 10.1089/pho.2007.2064
31. Hitz CB, Ewing JJ, Hecht J. Introduction to laser technology. 4th ed. Hoboken, NJ: John Wiley & Sons; 2012.
32. Ashmore J. Cochlear outer hair cell motility. Physiol Rev. 2008;88(1):173-210. doi: 10.1152/physrev.00044.2006
33. Jastreboff PJ, Jastreboff MM. Tinnitus retraining therapy: a different view on tinnitus. ORL J Otorhinolaryngol Relat Spec. 2006;68(1):23-30.
34. Davis PB, James LS, Mcsweeney BA, Laidlaw LE, Frater RH, Hanley PJ. Inventors; Neuromonics Pty Ltd, assignee. Tinnitus rehabilitation device and method. United States patent US 7,520,851. 2009 Apr 21.
35. Ricketts TA, Picou EM, Shehorn J, Dittberner AB. Degree of hearing loss affects bilateral hearing aid benefits in ecologically relevant laboratory conditions. J Speech Lang Hear Res. 2019;62(10):3834-50. doi: 10.1044/2019_JSLHR-H-19-0013
36. Shekhawat GS, Searchfield GD, Stinear CM. Role of hearing aids in tinnitus intervention: a scoping review. J Am Acad Audiol. 2013;24(8):747-62. doi: 10.3766/jaaa.24.8.11
37. Sereda M, McFerran D, Axon E, Baguley DM, Hall DA, Potgieter I, et al. A process for prioritising systematic reviews in tinnitus. Int J Audiol. 2020;59(8):640-6. doi: 10.1080/14992027.2020.1733677
38. Brueggemann P, Szczepek AJ, Seydel C, Schaefer C, Szczepek A, Amarjargal N, et al. ICD-10 symptom rating questionnaire for assessment of psychological comorbidities in patients with chronic tinnitus. HNO. 2019;67(3):178-83. doi: 10.1007/s00106-019-0618-6
39. Kumar Reddy KV, Chaitanya VK, Babu GR. Efficacy of tinnitus retraining therapy, a modish management of tinnitus: our experience. Indian J Otolaryngol Head Neck Surg. 2019;71(1):95-8. doi: 10.1007/s12070-018-1392-6
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| Issue | Vol 30 No 3 (2021) | |
| Section | Research Article(s) | |
| DOI | https://doi.org/10.18502/avr.v30i3.6535 | |
| Keywords | ||
| Tinnitus low-level laser therapy tinnitus retraining therapy tinnitus handicap inventory loudness matching visual analog scale | ||
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How to Cite
1.
Eyvazi M, Cheraghipour P, Irani M, Aarabi S, Fakhri J. A comparative study on photobiological effects of low-level laser therapy and tinnitus retraining therapy in patients with acoustic trauma-induced tinnitus. Aud Vestib Res. 2021;30(3):209-219.
