Research Article

The capability of gap in noise detection in patients with multiple sclerosis


Background and Aim: The temporal processing is one of the critical features in central auditory processing system; the gap in noise (GIN) test is the appropriate clinical tool for appraisal of temporal resolution which in people with multiple sclerosis may encounter with complications. Consequently, the aim of this study was to compare the results of gap in noise test in 18 to 40-year-old patients with multiple sclerosis and normal participants.
Methods: This cross-sectional non-invasive cohort study was conducted on 20 patients with relapsingremitting multiple sclerosis (mean age: 28.9 years) and 26 healthy normal hearing participant (mean age: 27.7 years) in the age range 18 to 40 years. The approximate threshold and percent of corrected responses were obtained and then were analyzed using Student’s t-test.
Results: There was an increase in gap detection and decrease in percent of corrected responses in gap in noise test within multiple sclerosis patients in comparison with normal people (p<0.0001). Moreover, there were a correlation of 78% between increasing disease duration and approximate threshold and also a correlation of 82% between increasing disease duration and corrected responses (p<0.0001).
Conclusion: Based on the findings of this study, it seems that people with multiple sclerosis suffer from some degree of disorder in the temporal resolution which might be due to involvement of central nerve system and, somehow, deficit in central auditory processing. Therefore, for evaluating the temporal resolution in people with multiple sclerosis, gap in noise test could be useful.

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IssueVol 21 No 4 (2012) QRcode
SectionResearch Article(s)
Central auditory processing temporal resolution gaps in noise multiple sclerosis

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Valadbeigi A, Rouhbakhsh N, Mohammadkhani G, Jalilvand Karimi L, Jalaie S. The capability of gap in noise detection in patients with multiple sclerosis. Aud Vestib Res. 21(4):10-18.