Ocular vestibular evoked myogenic potentials in normal-hearing adults

  • Maryam Ramezani Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran
  • Abdoreza Sheibanizade Mail Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran
  • Akram Pourbakht Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran
  • Homa Zarinkoub Department of Audiology, Faculty of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Mohammad Kamali Department of Rehabilitation Management, School of Rehabilitation, Tehran University of Medical Sciences, Iran
  • Seyede Nazanin Hajari Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Iran
Keywords:
Vestibule, ocular vestibular-evoked myogenic potentials, cervical vestibular-evoked myogenic potentials

Abstract

Background and Aim: Ocular vestibular-evoked myogenic potential (oVEMP) is a novel vestibular function test. This short-latency response can be recorded through contracting extraocular muscles by high-intensity acoustic stimulation and can be used to evaluate contralateral ocular-vestibular reflex. The aim of this study was to record and compare the amplitude, latency, asymmetry ratio and occurrence percentage of oVEMP (n10) and cervical VEMP (p13) responses in a group of normal adult subjects.
Methods: We carried out a cross-sectional study on 20 adult subjects’ mean age 22.18 years, SD=2.19 with normal hearing sensitivity and no history of vestibular diseases. oVEMP and cVEMP responses in both ears were recorded using air conducted stimuli 500 Hz short tone burst, 95 dB nHL via insert earphone and compared.
Results: cVEMP was recorded in all subjects but oVEMP was absent in two subjects. Mean amplitude and latency were 140.77 µv and 15.56 ms in p13; and 3.18 µv and 9.32 ms in n10. There were statistically significant differences between p13 and n10 amplitudes (p<0.001).
Conclusion: This study showed that occurrence percentage and amplitude of oVEMP were less than those of cVEMP. Since these two tests originate from different sections of vestibular nerve, we can consider them as parallel vestibular function tests and utilize them for evaluation of vestibular disorders.

References

1. Colebatch JG, Halmagyi GM, Skuse NF. Myogenic potentials generated by a click-evoked vestibulocollic reflex. J Neurol Neurosurg Psychiatry. 1994;57(2):190-97.
2. Rosengren SM, McAngus Todd NP, Colebatch JG. Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clin Neurophysiol. 2005;116(8):1938-48.
3. Chou CH, Wang SJ, Young YH. Feasibility of the simultaneous ocular and cervical vestibular-evoked myogenic potentials in unilateral vestibular hypofunction. Clin Neurophysiol. 2009;120(9):1699-705.
4. Iwasaki S, Murofushi T, Chihara Y, Ushio M, Suzuki M, Curthoys IS, et al. Ocular vestibular evoked myogenic potentials to bone-conduction vibration in vestibular schwannomas. Otol Neurotol. 2010;31(1):147-52.
5. Iwasaki S, Smulders YE, Burgess AM, McGarvie LA, Macdougall HG, Halmagyi GM, et al. Ocular vestibular evoked myogenic potentials to bone conducted vibration of the midline forehead at Fz in healthy subjects. Clin Neurophysiol. 2008;119(9):2135-47.
6. Smulders YE, Welgampola MS, Burgess AM, McGarvie LA, Halmagy GM, Curthoys IS. The n10 component of the ocular vestibular-evoked myogenic potential (oVEMP) is distinct from the R1 component of the blink reflex. Clin Neurophysiol. 2009;120(8):1567-76.
7. Park HJ, Lee IS, Shin JE, Lee YJ, Park MS. Frequency-tuning characteristics of cervical and ocular vestibular evoked myogenic potentials induced by air-conducted tone bursts. Clin Neurophysiol. 2010;121(1):85-9.
8. Sheykholeslami K, Murofushi T, Kaga K. The effect of sternocleidomastoeid electrode location on vestibular evoked myogenic potential. Auris Nasus larynx. 2001;28(1):41-3.
9. Wang SJ, Jaw FS, Young YH. Ocular vestibular-evoked myogenic potentials elicited from monaural versus binaural acoustic stimulations. Clin Neurophysiol. 2009;120(2):420-3.
10. Wang SJ, Weng WJ, Jaw FS, Young YH. Ocular and cervical vestibular-evoked myogenic potentials: a study to determine whether air- or bone-conducted stimuli are optimal. Ear Hear. 2010;31(2):283-8.
11. Cheng PW, Chen CC, Wang SJ, Young YH. Acoustic, mechanical and galvanic stimulation modes elicit ocular vestibular-evoked myogenic potentials. Clin Neurophysiol. 2009;120(10):1841-4.
12. Rosengren SM, Welgampola MS, Colebatch JG. Vestibular evoked myogenic potentials: past, present and future. Clin Neurophysiol. 2010;121(5):636-51.
13. Todd NP, Rosengren SM, Aw ST, Colebatch JG. Ocular vestibular evoked myogenic potentials (OVEMP) produced by air- and bone-conducted sound. Clin Neurophysiol. 2007;118(2):381-90.
14. Chihara Y, Iwasaki S, Ushio M, Murofushi T. Vestibular-evoked extraocular potentials by air-conducted sound: another clinical test for vestibular function. Clin Neurophysiol. 2007;118(12):2745-51.
15. Govender S, Rosengren SM, Colebatch JG. The effect of gaze direction on the ocular vestibular evoked myogenic potential produced by air-conducted sound. Clin Neurophysiol. 2009;120(7):1386-91.
Published
2017-07-31
How to Cite
1.
Ramezani M, Sheibanizade A, Pourbakht A, Zarinkoub H, Kamali M, Hajari SN. Ocular vestibular evoked myogenic potentials in normal-hearing adults. Aud Vestib Res. 21(2):42-49.
Section
Research Article(s)