The Role of Attention Modulation and Its Neurophysiological Mechanisms in Tinnitus Management: A Review
,
Abstract
Background and Aim: Tinnitus, characterized by the perception of sound without the presence of an external auditory stimulus, can profoundly affect the quality of life. This review study aims to assess the role of attention modulation in tinnitus management and investigate the neurophysiological mechanism of attention and its interaction with emotional processing in patients with tinnitus.
Recent Findings: The studies revealed differences in the function of attentional networks among individuals with tinnitus. The studies showed the positive impact of various techniques for attention modulation through direct attention training or indirect mechanisms influencing attention. These techniques could modify attentional biases, enhance attention control, and alleviate tinnitus-related distress.
Conclusion: The results of studies suggest the potential role of attention modulation in tinnitus management. By targeting attentional processes, researchers and clinicians can provide more effective interventions for individuals with tinnitus. However, there is a need for further investigation to optimize the intervention protocols by collaboration between researchers, clinicians, and individuals with tinnitus to achieve success in tinnitus management.
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29. Chen YC, Feng Y, Xu JJ, Mao CN, Xia W, Ren J, et al. Disrupted Brain Functional Network Architecture in Chronic Tinnitus Patients. Front Aging Neurosci. 2016;8:174.
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35. Vanneste S, De Ridder D. The auditory and non-auditory brain areas involved in tinnitus. An emergent property of multiple parallel overlapping subnetworks. Front Syst Neurosci. 2012;6:31. [DOI:10.3389/fnsys.2012.00031]
36. Wise KJ. Tinnitus and Attention Training. [Doctoral Theses]. Auckland: The University of Auckland; 2012.
37. Searchfield GD, Morrison-Low J, Wise K. Object identification and attention training for treating tinnitus. Prog Brain Res. 2007;166:441-60. [DOI:10.1016/S0079-6123(07)66043-9]
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40. Baguley DM. Mechanisms of tinnitus. Br Med Bull. 2002;63:195-212. [DOI:10.1093/bmb/63.1.195]
41. Boecking B, Rausch L, Psatha S, Nyamaa A, Dettling-Papargyris J, Funk C, et al. Hearing Therapy Improves Tinnitus-Related Distress in Mildly Distressed Patients with Chronic Tinnitus and Mild-to-Moderate Hearing Loss: A Randomized-Controlled Cross-Over Design. J Clin Med. 2022;11(7):1764. [DOI:10.3390/jcm11071764]
42. McKenna L, Marks EM, Vogt F. Mindfulness-Based Cognitive Therapy for Chronic Tinnitus: Evaluation of Benefits in a Large Sample of Patients Attending a Tinnitus Clinic. Ear Hear. 2018;39(2):359-66. [DOI:10.1097/AUD.0000000000000491]
43. Zimmerman B, Finnegan M, Paul S, Schmidt S, Tai Y, Roth K, et al. Functional Brain Changes During Mindfulness-Based Cognitive Therapy Associated With Tinnitus Severity. Front Neurosci. 2019;13:747. [DOI:10.3389/fnins.2019.00747]
44. Wise K, Kobayashi K, Magnusson J, Welch D, Searchfield GD. Randomized Controlled Trial of a Perceptual Training Game for Tinnitus Therapy. Games Health J. 2016;5(2):141-9. [DOI:10.1089/g4h.2015.0068]
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51. Wei X, Lv H, Wang Z, Liu C, Ren P, Zhang P, et al. Neuroanatomical Alterations in Patients With Tinnitus Before and After Sound Therapy: A Voxel-Based Morphometry Study. Front Neurosci. 20208;14:911. [DOI:10.3389/fnins.2020.00911]
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2. McCormack A, Edmondson-Jones M, Somerset S, Hall D. A systematic review of the reporting of tinnitus prevalence and severity. Hear Res. 2016;337:70-9. [DOI:10.1016/j.heares.2016.05.009]
3. Acharya, D. An Overview of Tinnitus (The Humming Ear): Epidemiology and Pathophysiology. In: Murdaca G, editor. Research Highlights in Disease and Health Research Vol. 3. India: B P International; 2023. p. 107-21.
4. Roberts LE, Husain FT, Eggermont JJ. Role of attention in the generation and modulation of tinnitus. Neurosci Biobehav Rev. 2013;37(8):1754-73. [DOI:10.1016/j.neubiorev.2013.07.007]
5. Posner MI. Attention: the mechanisms of consciousness. Proc Natl Acad Sci U S A. 1994;91(16):7398-403. [DOI:10.1073/pnas.91.16.7398]
6. Petersen SE, Posner MI. The attention system of the human brain: 20 years after. Annu Rev Neurosci. 2012;35:73-89. [DOI:10.1146/annurev-neuro-062111-150525]
7. Mohsen S, Pourbakht A. An overview of the tinnitus network activity and its clinical implications. Aud Vestib Res. 2018;27(4):171-8. [DOI:10.18502/avr.v27i4.121]
8. Henry JL, Wilson PH. The Psychological Management of Chronic Tinnitus: A Cognitive-behavioral Approach. Boston: Allyn and Bacon; 2001.
9. Posner MI, Petersen SE. The attention system of the human brain. Annu Rev Neurosci. 1990;13:25-42. [DOI:10.1146/annurev.ne.13.030190.000325]
10. Schecklmann M, Lehner A, Poeppl TB, Kreuzer PM, Rupprecht R, Rackl J, et al. Auditory cortex is implicated in tinnitus distress: a voxel-based morphometry study. Brain Struct Funct. 2013;218(4):1061-70. [DOI:10.1007/s00429-013-0520-z]
11. Hu J, Cui J, Xu JJ, Yin X, Wu Y, Qi J. The Neural Mechanisms of Tinnitus: A Perspective From Functional Magnetic Resonance Imaging. Front Neurosci. 2021;15:621145. [DOI:10.3389/fnins.2021.621145]
12. Kok TE, Domingo D, Hassan J, Vuong A, Hordacre B, Clark C, et al. Resting-state Networks in Tinnitus: A Scoping Review. Clin Neuroradiol. 2022;32(4):903-22. [DOI:10.1007/s00062-022-01170-1]
13. Desimone R, Duncan J. Neural mechanisms of selective visual attention. Annu Rev Neurosci. 1995;18:193-222. [DOI:10.1146/annurev.ne.18.030195.001205]
14. Rauschecker JP, Leaver AM, Mühlau M. Tuning out the noise: limbic-auditory interactions in tinnitus. Neuron. 2010;66(6):819-26. [DOI:10.1016/j.neuron.2010.04.032]
15. Friston K. A theory of cortical responses. Philos Trans R Soc Lond B Biol Sci. 2005;360(1456):815-36. [DOI:10.1098/rstb.2005.1622]
16. Coombes SA, Higgins T, Gamble KM, Cauraugh JH, Janelle CM. Attentional control theory: anxiety, emotion, and motor planning. J Anxiety Disord. 2009;23(8):1072-9. [DOI:10.1016/j.janxdis.2009.07.009]
17. De Ridder D, Elgoyhen AB, Romo R, Langguth B. Phantom percepts: tinnitus and pain as persisting aversive memory networks. Proc Natl Acad Sci U S A. 2011;108(20):8075-80. [DOI:10.1073/pnas.1018466108]
18. Elgoyhen AB, Langguth B, De Ridder D, Vanneste S. Tinnitus: perspectives from human neuroimaging. Nat Rev Neurosci. 2015;16(10):632-42. [DOI:10.1038/nrn4003]
19. Leaver AM, Renier L, Chevillet MA, Morgan S, Kim HJ, Rauschecker JP. Dysregulation of limbic and auditory networks in tinnitus. Neuron. 2011;69(1):33-43. [DOI:10.1016/j.neuron.2010.12.002]
20. Comte M, Schön D, Coull JT, Reynaud E, Khalfa S, Belzeaux R, et al. Dissociating Bottom-Up and Top-Down Mechanisms in the Cortico-Limbic System during Emotion Processing. Cereb Cortex. 2016;26(1):144-55. [DOI:10.1093/cercor/bhu185]
21. Adjamian P, Sereda M, Hall DA. The mechanisms of tinnitus: perspectives from human functional neuroimaging. Hear Res. 2009;253(1-2):15-31. [DOI:10.1016/j.heares.2009.04.001]
22. Jensen M, Hüttenrauch E, Müller-Mazzotta J, Stuck BA, Weise C. On the impairment of executive control of attention in chronic tinnitus: Evidence from the attention network test. Behav Brain Res. 2021;414:113493. [DOI:10.1016/j.bbr.2021.113493]
23. Leong SL, Tchen S, Robertson IH, Alsalman O, To WT, Vanneste S. The potential interruptive effect of tinnitusrelated distress on attention. Sci Rep. 2020;10(1):11911. [DOI:10.1038/s41598-020-68664-1]
24. Schlee W, Hartmann T, Langguth B, Weisz N. Abnormal resting-state cortical coupling in chronic tinnitus. BMC Neurosci. 2009;10:11. [DOI:10.1186/1471-2202-10-11]
25. Husain FT. Neural networks of tinnitus in humans: Elucidating severity and habituation. Hear Res. 2016;334:37-48. [DOI:10.1016/j.heares.2015.09.010]
26. Schlee W, Mueller N, Hartmann T, Keil J, Lorenz I, Weisz N. Mapping cortical hubs in tinnitus. BMC Biol. 2009;7:80. [DOI:10.1186/1741-7007-7-80]
27. Husain FT, Medina RE, Davis CW, Szymko-Bennett Y, Simonyan K, Pajor NM, et al. Neuroanatomical changes due to hearing loss and chronic tinnitus: a combined VBM and DTI study. Brain Res. 2011;1369:74-88. [DOI:10.1016/j.brainres.2010.10.095]
28. Mohsen S, Mahmoudian S, Talebian S, Pourbakht A. Multisite transcranial Random Noise Stimulation (tRNS) modulates the distress network activity and oscillatory powers in subjects with chronic tinnitus. J Clin Neurosci. 2019;67:178-84. [DOI:10.1016/j.jocn.2019.06.033]
29. Chen YC, Feng Y, Xu JJ, Mao CN, Xia W, Ren J, et al. Disrupted Brain Functional Network Architecture in Chronic Tinnitus Patients. Front Aging Neurosci. 2016;8:174.
30. Roberts LE, Eggermont JJ, Caspary DM, Shore SE, Melcher JR, Kaltenbach JA. Ringing ears: the neuroscience of tinnitus. J Neurosci. 2010;30(45):14972-9. [DOI:10.1523/JNEUROSCI.4028-10.2010]
31. Corbetta M, Shulman GL. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci. 2002;3(3):201-15. [DOI:10.1038/nrn755]
32. Fox MD, Corbetta M, Snyder AZ, Vincent JL, Raichle ME. Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci U S A. 2006;103(26):10046-51. [DOI:10.1073/pnas.0604187103]
33. Husain FT, Schmidt SA. Using resting state functional connectivity to unravel networks of tinnitus. Hear Res. 2014;307:153-62. [DOI:10.1016/j.heares.2013.07.010]
34. Chen YC, Li X, Liu L, Wang J, Lu CQ, Yang M, et al. Tinnitus and hyperacusis involve hyperactivity and enhanced connectivity in auditory-limbic-arousal-cerebellar network. Elife. 2015;4:e06576. [DOI:10.7554/eLife.06576]
35. Vanneste S, De Ridder D. The auditory and non-auditory brain areas involved in tinnitus. An emergent property of multiple parallel overlapping subnetworks. Front Syst Neurosci. 2012;6:31. [DOI:10.3389/fnsys.2012.00031]
36. Wise KJ. Tinnitus and Attention Training. [Doctoral Theses]. Auckland: The University of Auckland; 2012.
37. Searchfield GD, Morrison-Low J, Wise K. Object identification and attention training for treating tinnitus. Prog Brain Res. 2007;166:441-60. [DOI:10.1016/S0079-6123(07)66043-9]
38. Spiegel DP, Linford T, Thompson B, Petoe MA, Kobayashi K, Stinear CM, et al. Multisensory attention training for treatment of tinnitus. Sci Rep. 2015;5:10802. [DOI:10.1038/srep10802]
39. Cima R, Joore M, Maes I, Scheyen D, Refaie AE, Baguley DM, et al. Cost-effectiveness of multidisciplinary management of Tinnitus at a specialized Tinnitus centre. BMC Health Serv Res. 2009;9:29. [DOI:10.1186/1472-6963-9-29]
40. Baguley DM. Mechanisms of tinnitus. Br Med Bull. 2002;63:195-212. [DOI:10.1093/bmb/63.1.195]
41. Boecking B, Rausch L, Psatha S, Nyamaa A, Dettling-Papargyris J, Funk C, et al. Hearing Therapy Improves Tinnitus-Related Distress in Mildly Distressed Patients with Chronic Tinnitus and Mild-to-Moderate Hearing Loss: A Randomized-Controlled Cross-Over Design. J Clin Med. 2022;11(7):1764. [DOI:10.3390/jcm11071764]
42. McKenna L, Marks EM, Vogt F. Mindfulness-Based Cognitive Therapy for Chronic Tinnitus: Evaluation of Benefits in a Large Sample of Patients Attending a Tinnitus Clinic. Ear Hear. 2018;39(2):359-66. [DOI:10.1097/AUD.0000000000000491]
43. Zimmerman B, Finnegan M, Paul S, Schmidt S, Tai Y, Roth K, et al. Functional Brain Changes During Mindfulness-Based Cognitive Therapy Associated With Tinnitus Severity. Front Neurosci. 2019;13:747. [DOI:10.3389/fnins.2019.00747]
44. Wise K, Kobayashi K, Magnusson J, Welch D, Searchfield GD. Randomized Controlled Trial of a Perceptual Training Game for Tinnitus Therapy. Games Health J. 2016;5(2):141-9. [DOI:10.1089/g4h.2015.0068]
45. Kallogjeri D, Piccirillo JF, Spitznagel E Jr, Hale S, Nicklaus JE, Hardin FM, et al. Cognitive Training for Adults With Bothersome Tinnitus: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2017;143(5):443-51. [DOI:10.1001/jamaoto.2016.3779]
46. Busse M, Low YF, Corona-Strauss FI, Delb W, Strauss DJ. Neurofeedback by neural correlates of auditory selective attention as possible application for tinnitus therapies. Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:5136-9. [DOI:10.1109/IEMBS.2008.4650370]
47. Smith JA, Mennemeier M, Bartel T, Chelette KC, Kimbrell T, Triggs W, et al. Repetitive transcranial magnetic stimulation for tinnitus: a pilot study. Laryngoscope. 2007;117(3):529-34. [DOI:10.1097/MLG.0b013e31802f4154]
48. Kan Y, Wang W, Zhang SX, Ma H, Wang ZC, Yang JG. Neural metabolic activity in idiopathic tinnitus patients after repetitive transcranial magnetic stimulation. World J Clin Cases. 2019;7(13):1582-90. [DOI:10.12998/wjcc.v7.i13.1582]
49. Leaver AM, Chen YJ, Parrish TB. Focal tDCS of auditory cortex in chronic tinnitus: A randomized controlled mechanistic trial. Clin Neurophysiol. 2023;158:79-91. [DOI:10.1016/j.clinph.2023.11.021]
50. Shahsavarani S, Khan RA, Husain FT. Tinnitus and the brain: a review of functional and anatomical magnetic resonance imaging studies. Perspectives of the ASHA Special Interest Groups. 2019;4(5):896-909. https://pubs.asha.org/doi/10.1044/2019_PERS-SIG6-2019-0001
51. Wei X, Lv H, Wang Z, Liu C, Ren P, Zhang P, et al. Neuroanatomical Alterations in Patients With Tinnitus Before and After Sound Therapy: A Voxel-Based Morphometry Study. Front Neurosci. 20208;14:911. [DOI:10.3389/fnins.2020.00911]
52. Eggermont JJ, Tass PA. Maladaptive neural synchrony in tinnitus: origin and restoration. Front Neurol. 2015;6:29. [DOI:10.3389/fneur.2015.00029]
53. Chen YC, Wang F, Wang J, Bo F, Xia W, Gu JP, et al. Resting-State Brain Abnormalities in Chronic Subjective Tinnitus: A Meta-Analysis. Front Hum Neurosci. 2017;11:22. [DOI:10.3389/fnhum.2017.00022]
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| Files | ||
| Issue | Vol 33 No 3 (2024) | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/avr.v33i3.15499 | |
| Keywords | ||
| Tinnitus attention tinnitus management neurophysiological mechanism attention training | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Namvar Arefi H, Jarollahi F, Mohsen SM, Jalaie S. The Role of Attention Modulation and Its Neurophysiological Mechanisms in Tinnitus Management: A Review. Aud Vestib Res. 2024;33(3):184-193.
