Research Article

Exploring the Effects of Alternate Auditory Attention Tasks on Electromotility of Cochlear Outer Hair Cells in Healthy Normal Hearing Adults

Abstract

Background and Aim: There is limited study on the role of rostral efferent auditory pathway on Outer Hair Cell (OHC) activity. We investigated the effect of integrating alternate auditory attention (ALAUDIN©) tasks with White Noise (WN) and its reliability using contralateral suppression of Transient Evoked Otoacoustic Emission (TEOAE).
Methods: This study was conducted at the Audiology Clinic, Universiti Kebangsaan Malaysia, with fifty normal-hearing adults. All subjects underwent standard audiological testing to ensure normal hearing, middle ear, and cochlear function. Contralateral suppressors with and without attention tasks were delivered randomly to the non-test ear while simultaneously measuring TEOAE amplitude in the test ear to investigate the effect of auditory attention on OHC electromotility. Suppressors with and without attention refer to the combination of a 1000 Hz tone and speech stimulus embedded in WN and WN alone, respectively. Subsequently, the difference in TEOAE amplitude during the presence and absence of suppressors was calculated, and thus suppression magnitude was determined.
Results: Intraclass correlation revealed that 4 suppressors produced high reliability. In paired sample t-tests, the tasks significantly reduced the amplitude of the TEOAE in the right ear compared to the left ear (p<0.05). However, the suppression magnitude did not differ significantly between ears (p>0.05). Descriptively, females showed greater TEOAE suppression.
Conclusion: This study demonstrated that directing ALAUDIN© tasks to one ear can affect OHC electromotility, as evidenced by TEOAE amplitude changes, but it did not impact the overall suppression magnitude. Additionally, it hinted at potential gender differences in TEOAE suppression, warranting further investigation.

1. Kemp DT. Otoacoustic Emissions: Concepts and Origins. In: Manley GA, Fay RR, Popper AN, editors. Active Processes and Otoacoustic Emissions in Hearing. New York: Springer; 2007. p. 1-38.
2. Kemp DT. Otoacoustic emissions, their origin in cochlear function, and use. Br Med Bull. 2002;63:223-41. [DOI:10.1093/bmb/63.1.223]
3. Harkrider AW, Bowers CD. Evidence for a cortically mediated release from inhibition in the human cochlea. J Am Acad Audiol. 2009;20(3):208-15. [DOI:10.3766/jaaa.20.3.7]
4. Ugur AK, Kemaloglu YK, Ugur MB, Gunduz B, Saridogan C, Yesilkaya E, et al. Otoacoustic emissions and effects of contralateral white noise stimulation on transient evoked otoacoustic emissions in diabetic children. Int J Pediatr Otorhinolaryngol. 2009;73(4):555-9. [DOI:10.1016/j.ijporl.2008.12.002]
5. Stuart A, Cobb KM. Reliability of measures of transient evoked otoacoustic emissions with contralateral suppression. J Commun Disord. 2015;58:35-42. [DOI:10.1016/j.jcomdis.2015.09.003]
6. Prasher D, Ryan S, Luxon L. Contralateral suppression of transiently evoked otoacoustic emissions and neuro-otology. Br J Audiol. 1994;28(4-5):247-54. [DOI:10.3109/03005369409086574]
7. Maison S, Micheyl C, Collet L. Influence of focused auditory attention on cochlear activity in humans. Psychophysiology. 2001;38(1):35-40. [DOI:10.1111/1469-8986.3810035]
8. Perrot X, Ryvlin P, Isnard J, Guénot M, Catenoix H, Fischer C, et al. Evidence for corticofugal modulation of peripheral auditory activity in humans. Cereb Cortex. 2006;16(7):941-8. [DOI:10.1093/cercor/bhj035]
9. Abdul Wahab NA, Wahab S, Abdul Rahman AH, Sidek D, Zakaria MN. The Hyperactivity of Efferent Auditory System in Patients with Schizophrenia: A Transient Evoked Otoacoustic Emissions Study. Psychiatry Investig. 2016;13(1):82-8. [DOI:10.4306/pi.2016.13.1.82]
10. Pereira VR, Feitosa MÂ, Pereira LH, Azevedo MF. Role of the medial olivocochlear system among children with ADHD. Braz J Otorhinolaryngol. 2012;78(3):27-31. [DOI:10.1590/S1808-86942012000300006]
11. Albajara Sáenz A, Septier M, Van Schuerbeek P, Baijot S, Deconinck N, Defresne P, et al. ADHD and ASD: distinct brain patterns of inhibition-related activation? Transl Psychiatry. 2020;10(1):24. [DOI:10.1038/s41398-020-0707-z]
12. Jedrzejczak WW, Milner R, Ganc M, Pilka E, Skarzynski H. No Change in Medial Olivocochlear Efferent Activity during an Auditory or Visual Task: Dual Evidence from Otoacoustic Emissions and Event-Related Potentials. Brain Sci. 2020;10(11):894. [DOI:10.3390/brainsci10110894]
13. Francis NA, Zhao W, Guinan JJ Jr. Auditory Attention Reduced Ear-Canal Noise in Humans by Reducing Subject Motion, Not by Medial Olivocochlear Efferent Inhibition: Implications for Measuring Otoacoustic Emissions During a Behavioral Task. Front Syst Neurosci. 2018;12:42. [DOI:10.3389/fnsys.2018.00042]
14. Mattsson TS, Lind O, Follestad T, Grøndahl K, Wilson W, Nordgård S. Contralateral suppression of otoacoustic emissions in a clinical sample of children with auditory processing disorder. Int J Audiol. 2019;58(5):301-10. [DOI:10.1080/14992027.2019.1570358]
15. Greaves IJ. CUNY Academic Works Associations of the Medial Olivocochlear Reflex and Speech-In-Noise Abilities in Normal Hearing Adult Listeners : A Systematic Review. CUNY Academic Works. Available from https://academicworks.cuny.edu/gc_etds/2649
16. Hiscock M, Kinsbourne M. Attention and the rightear advantage: what is the connection? Brain Cogn. 2011;76(2):263-75. [DOI:10.1016/j.bandc.2011.03.016]
17. Jedrzejczak WW, Milner R, Pilka E, Ganc M, Skarzynski H. Easy and Hard Auditory Tasks Distinguished by Otoacoustic Emissions and Event-related Potentials: Insights into Efferent System Activity. Neuroscience. 2022;491:87-97. [DOI:10.1016/j.neuroscience.2022.03.029]
18. Zamiri Abdollahi F, Lotfi Y. Gender Difference in TEOAEs and Contralateral Suppression of TEOAEs in Normal Hearing Adults. Iranian Rehabilitation Journal. 2011;9(2):22-5.
19. Tomasi D, Volkow ND. Abnormal functional connectivity in children with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2012;71(5):443-50. [DOI:10.1016/j.biopsych.2011.11.003]
20. Jedrzejczak WW, Pilka E, Pastucha M, Kochanek K, Skarzynski H. The Reliability of Contralateral Suppression of Otoacoustic Emissions Is Greater in Women than in Men. Audiol Res. 2022;12(1):79-86. [DOI:10.3390/audiolres12010008]
21. Jedrzejczak WW, Pilka E, Olszewski L, Skarzynski H. Short-Term Repeatability of Contralateral Suppression of Transiently Evoked Otoacoustic Emissions: Preliminary Results. J Hear Sci. 2016;6(2):51-7. [DOI:10.17430/899578]
22. Naglieri JA, Rojahn J. (2001). Gender differences in planning, attention, simultaneous, and successive (PASS) cognitive processes and achievement. J Educ Psychol. 2001;93(2):430-7. [DOI:10.1037/0022-0663.93.2.430]
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IssueVol 33 No 2 (2024) QRcode
SectionResearch Article(s)
DOI https://doi.org/10.18502/avr.v33i2.14817
Keywords
Suppression otoacoustic emissions efferent pathway auditory attention
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How to Cite
1.
Tahir SAM, Awang CMAC, Wahab NAA, Zakaria MN, Wahab S, Wahat NHA, Maamor N. Exploring the Effects of Alternate Auditory Attention Tasks on Electromotility of Cochlear Outer Hair Cells in Healthy Normal Hearing Adults. Aud Vestib Res. 2023;33(2):142-151.