Evaluation of Synaptopathy by Use of Latency Shift of Wave V Auditory Brainstem Response in the Presence of Ipsilateral Noise
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Abstract
Background and Aim: Recreational and occupational noise can cause permanent damage to the inner ear. Cochlear synaptopathy can be “hidden” because this synaptic reduction can occur without permanent hearing threshold changes. Our study aimed to assess synaptopathy in people with and without a history of occupational noise exposure by use of latency shift of wave V with masking.
Methods: In this study, 38 males were involved. All participants had normal hearing thresholds. Of 38 males, 20-male identified with exposure to occupational noise and 18 identified without occupational noise exposure. Auditory brainstem response and masked were performed.
Results: The main effect of the between-group factor was not significant in the right and left ears. But the main effect of the within-group factor in the right and left ears were significant (p<0.001 and p<0.001). Auditory brainstem response latencies at different levels in each group were significant. These results showed that there were no significant differences between latency changes in both groups.
Conclusion: In order to diagnose cochlear synaptopathy in humans it is important to use audiological test batteries in the future. There is currently no effective way to diagnose noiseinduced cochlear synaptopathy in human subjects.
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[9] Lin HW, Furman AC, Kujawa SG, Liberman MC. Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift. J Assoc Res Otolaryngol. 2011;12(5):605-16. [DOI:10.1007/s10162-011-0277-0]
[10] Cooper JC Jr, Gates GA. Hearing in the elderly—the Framingham cohort, 1983-1985: Part II. Prevalence of central auditory processing disorders. Ear Hear. 1991;12(5):304-11. [DOI:10.1097/00003446-199110000-00002]
[11] Barbee CM, James JA, Park JH, Smith EM, Johnson CE, Clifton S, et al. Effectiveness of Auditory Measures for Detecting Hidden Hearing Loss and/or Cochlear Synaptopathy: A Systematic Review. Semin Hear. 2018;39(2):172-209. [DOI:10.1055/s-0038-1641743]
[12] Aedo C, Aguilar E. Cochlear synaptopathy: new findings in animal and human research. Rev Neurosci. 2020;31(6):605-15. [DOI:10.1515/revneuro-2020-0002]
[13] Bramhall N, Beach EF, Epp B, Le Prell CG, Lopez-Poveda EA, Plack CJ, et al. The search for noise-induced cochlear synaptopathy in humans: Mission impossible? Hear Res. 2019;377:88-103. [DOI:10.1016/j.heares.2019.02.016]
[14] Attias J, Pratt H. Auditory evoked potentials and audiological follow-up of subjects developing noise-induced permanent threshold shift. Audiology. 1984;23(5):498-508. [DOI:10.3109/00206098409070089]
[15] Almadori G, Ottaviani F, Paludetti G, Rosignoli M, Gallucci L, D’Alatri L, et al. Auditory brainstem responses in noiseinduced permanent hearing loss. Audiology. 1988;27(1):36-41. [DOI:10.3109/00206098809081572]
[16] Liberman LD, Suzuki J, Liberman MC. Dynamics of cochlear synaptopathy after acoustic overexposure. J Assoc Res Otolaryngol. 2015;16(2):205-19 [DOI:10.1007/s10162-015-0510-3]
[17] Shaheen LA, Valero MD, Liberman MC. Towards a Diagnosis of Cochlear Neuropathy with Envelope Following Responses. J Assoc Res Otolaryngol. 2015;16(6):727-45. [DOI:10.1007/s10162-015-0539-3]
[18] Stamper GC, Johnson TA. Auditory function in normalhearing, noise-exposed human ears. Ear Hear. 2015;36(2):172-84. [DOI:10.1097/AUD.0000000000000107]
[19] Bramhall NF, Konrad-Martin D, McMillan GP, Griest SE. Auditory Brainstem Response Altered in Humans With Noise Exposure Despite Normal Outer Hair Cell Function. Ear Hear. 2017;38(1):e1-12. [DOI:10.1097/AUD.0000000000000370]
[20] Liberman MC, Epstein MJ, Cleveland SS, Wang H, Maison SF. Toward a Differential Diagnosis of Hidden Hearing Loss in Humans. PLoS One. 2016;11(9):e0162726. [DOI:10.1371/journal.pone.0162726]
[21] Valderrama JT, Beach EF, Yeend I, Sharma M, Van Dun B, Dillon H. Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-innoise intelligibility. Hear Res. 2018;365:36-48. [DOI:10.1016/j.heares.2018.06.003]
[22] Kujawa SG, Liberman MC. Adding insult to injury: cochlear nerve degeneration after “temporary” noise-induced hearing loss. J Neurosci. 2009;29(45):14077-85. [DOI:10.1523/JNEUROSCI.2845-09.2009]
[23] Borg E, Canlon B, Engström B. Noise-induced hearing loss. Literature review and experiments in rabbits. Morphological and electrophysiological features, exposure parameters and temporal factors, variability and interactions. Scand Audiol Suppl. 1995;40:1-147.
[2] Anderson S, Kraus N. Neural Encoding of Speech and Music: Implications for Hearing Speech in Noise. Semin Hear. 2011;32(2):129-41. [DOI:10.1055/s-0031-1277234]
[3] Prendergast G, Tu W, Guest H, Millman RE, Kluk K, Couth S, et al. Supra-threshold auditory brainstem response amplitudes in humans: Test-retest reliability, electrode montage and noise exposure. Hear Res. 2018;364:38-47. [DOI:10.1016/j.heares.2018.04.002]
[4] Mehraei G, Hickox AE, Bharadwaj HM, Goldberg H, Verhulst S, Liberman MC, et al. Auditory Brainstem Response Latency in Noise as a Marker of Cochlear Synaptopathy. J Neurosci. 2016;36(13):3755-64. [DOI:10.1523/JNEUROSCI.4460-15.2016]
[5] Schmiedt RA, Mills JH, Boettcher FA. Age-related loss of activity of auditory-nerve fibers. J Neurophysiol. 1996;76(4):2799-803. [DOI:10.1152/jn.1996.76.4.2799]
[6] Furman AC, Kujawa SG, Liberman MC. Noise-induced cochlear neuropathy is selective for fibers with low spontaneous rates. J Neurophysiol. 2013;110(3):577-86. [DOI:10.1152/jn.00164.2013]
[7] Woellner Rc, Schuknecht Hf. Hearing loss from lesions of the cochlear nerve: an experimental and clinical study. Trans Am Acad Ophthalmol Otolaryngol. 1955;59(2):147-9.
[8] Costalupes JA, Young ED, Gibson DJ. Effects of continuous noise backgrounds on rate response of auditory nerve fibers in cat. J Neurophysiol. 1984;51(6):1326-44. [DOI:10.1152/jn.1984.51.6.1326]
[9] Lin HW, Furman AC, Kujawa SG, Liberman MC. Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift. J Assoc Res Otolaryngol. 2011;12(5):605-16. [DOI:10.1007/s10162-011-0277-0]
[10] Cooper JC Jr, Gates GA. Hearing in the elderly—the Framingham cohort, 1983-1985: Part II. Prevalence of central auditory processing disorders. Ear Hear. 1991;12(5):304-11. [DOI:10.1097/00003446-199110000-00002]
[11] Barbee CM, James JA, Park JH, Smith EM, Johnson CE, Clifton S, et al. Effectiveness of Auditory Measures for Detecting Hidden Hearing Loss and/or Cochlear Synaptopathy: A Systematic Review. Semin Hear. 2018;39(2):172-209. [DOI:10.1055/s-0038-1641743]
[12] Aedo C, Aguilar E. Cochlear synaptopathy: new findings in animal and human research. Rev Neurosci. 2020;31(6):605-15. [DOI:10.1515/revneuro-2020-0002]
[13] Bramhall N, Beach EF, Epp B, Le Prell CG, Lopez-Poveda EA, Plack CJ, et al. The search for noise-induced cochlear synaptopathy in humans: Mission impossible? Hear Res. 2019;377:88-103. [DOI:10.1016/j.heares.2019.02.016]
[14] Attias J, Pratt H. Auditory evoked potentials and audiological follow-up of subjects developing noise-induced permanent threshold shift. Audiology. 1984;23(5):498-508. [DOI:10.3109/00206098409070089]
[15] Almadori G, Ottaviani F, Paludetti G, Rosignoli M, Gallucci L, D’Alatri L, et al. Auditory brainstem responses in noiseinduced permanent hearing loss. Audiology. 1988;27(1):36-41. [DOI:10.3109/00206098809081572]
[16] Liberman LD, Suzuki J, Liberman MC. Dynamics of cochlear synaptopathy after acoustic overexposure. J Assoc Res Otolaryngol. 2015;16(2):205-19 [DOI:10.1007/s10162-015-0510-3]
[17] Shaheen LA, Valero MD, Liberman MC. Towards a Diagnosis of Cochlear Neuropathy with Envelope Following Responses. J Assoc Res Otolaryngol. 2015;16(6):727-45. [DOI:10.1007/s10162-015-0539-3]
[18] Stamper GC, Johnson TA. Auditory function in normalhearing, noise-exposed human ears. Ear Hear. 2015;36(2):172-84. [DOI:10.1097/AUD.0000000000000107]
[19] Bramhall NF, Konrad-Martin D, McMillan GP, Griest SE. Auditory Brainstem Response Altered in Humans With Noise Exposure Despite Normal Outer Hair Cell Function. Ear Hear. 2017;38(1):e1-12. [DOI:10.1097/AUD.0000000000000370]
[20] Liberman MC, Epstein MJ, Cleveland SS, Wang H, Maison SF. Toward a Differential Diagnosis of Hidden Hearing Loss in Humans. PLoS One. 2016;11(9):e0162726. [DOI:10.1371/journal.pone.0162726]
[21] Valderrama JT, Beach EF, Yeend I, Sharma M, Van Dun B, Dillon H. Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-innoise intelligibility. Hear Res. 2018;365:36-48. [DOI:10.1016/j.heares.2018.06.003]
[22] Kujawa SG, Liberman MC. Adding insult to injury: cochlear nerve degeneration after “temporary” noise-induced hearing loss. J Neurosci. 2009;29(45):14077-85. [DOI:10.1523/JNEUROSCI.2845-09.2009]
[23] Borg E, Canlon B, Engström B. Noise-induced hearing loss. Literature review and experiments in rabbits. Morphological and electrophysiological features, exposure parameters and temporal factors, variability and interactions. Scand Audiol Suppl. 1995;40:1-147.
| Files | ||
| Issue | Vol 32 No 1 (2023) | |
| Section | Research Article(s) | |
| DOI | https://doi.org/10.18502/avr.v32i1.11321 | |
| Keywords | ||
| Noise induce cochlear synaptopathy auditory brainstem response cochlear synaptopathy hidden hearing loss | ||
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How to Cite
1.
Sabzinasab Z, Rouzbahani M, Toufan R, Maarefvand M. Evaluation of Synaptopathy by Use of Latency Shift of Wave V Auditory Brainstem Response in the Presence of Ipsilateral Noise. Aud Vestib Res. 2023;32(1):47-53.
