Assessment of Saccular and Semicircular Canal’s Function in Behcet’s Disease
-
Zahra Heidari Sharifabad
,
Fahimeh Hajiabolhassan
,
Reza Hoseinabadi
,
Seyedeh Tahereh Faezi
,
Shohreh Jalaie
Abstract
Background and Aim: Behcet’s disease (BD) is a multisystemic, chronic and progressive disorder with a relatively high prevalence in Iran. Therefore, this study aimed to compare the vestibular function between Iranian BD patients and normal subjects using cervical vestibular- evoked myogenic potentials (cVEMPs) and video head impulse test (vHIT).
Methods: In this cross-sectional study, 44 patients with definitive BD in the inactive stage of disease and 30 age and sex matched normal subjects were evaluated via cVEMP and vHIT tests and dizziness handicap inventory (DHI). Then the parameters of the tests were compared between the two groups by statistical methods. Moreover, the effects of DHI scores and other contextual variables on the test results were examined.
Results: In terms of the cVEMP test, the response rate and mean latency of p13 in the left ear were significantly lower, the amplitude of the cVEMP wave in the left ear and the amplitude asymmetry ratio were significantly higher in BD patients compared to normal subjects (p<0.05). Fifteen BD patients had abnormal amplitude and nine patients had abnormal latency of cVEMP responses. In terms of the vHIT test, the mean vestibule-ocular reflex gain of the left posterior semicircular canal and the mean gain asymmetry ratio of lateral canals were significantly higher in BD patients than in the controls (p<0.05).
Conclusion: the vestibular system of some patients with BD is disturbed and the results of this study indicate the presence of unilateral vestibular weakness in BD. So vestibular assessment can be helpful for these patients.
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[12] Herdman SJ, Clendaniel R. Vestibular rehabilitation. Philadelphia: F. A. Davis Company; 2014.
[13] Kose E, Kamisli S, Dogan M, Tasolar S, Kahraman A, Oztanir MN, et al. The evaluation of vertebrobasilar artery system in neuro‐Behçet and Behçet disease using magnetic resonance angiography. Anat Rec. 2014;297(7):1302-5. [DOI:10.1002/ar.22922 ]
[14] Bayram A, Doğan M, Koç A, Kalkan M, Akçadağ A, Özcan İ. Cervical and ocular vestibular evoked myogenic potentials in Behcet’s disease. Am J Otolaryngol. 2015;36(4):503-8. [DOI:10.1016/j.amjoto.2015.03.004 ]
[15] Evereklioglu C, Cokkeser Y, Doganay S, Er H, Kizilay A. Audio-vestibular evaluation in patients with Behçet’s syndrome. J Laryngol Otol. 2001;115(9):704-8. [DOI:10.1258/0022215011908946]
[16] McCaslin DL, Jacobson GP. Vestibular-Evoked Myogenic Potentials (VEMPs). In: Jacobson GP, Shepard NT, editors. Balance Function Assessment and Management. 2nd ed. San Diego, CA: Plural Publishing; 2016. p. 533-79.
[17] Wuyts FL, Furman J, Vanspauwen R, Van de Heyning P. Vestibular function testing. Curr Opin Neurol. 2007;20(1):19-24. [DOI:10.1097/WCO.0b013e3280140808]
[18] Abdel Baki NM, Zahran AMA, Dabbous AO, Koura RA, Hamdy MM. Cervical vestibular evoked myogenic potential and high-frequency audiometry results in Behçet’s disease. Egypt Rheumatol Rehabil. 2021;48:3. [DOI:10.1186/s43166-020-00052-z]
[19] MacDougall HG, McGarvie LA, Halmagyi GM, Curthoys IS, Weber KP. Application of the video head impulse test to detect vertical semicircular canal dysfunction. Otol Neurotol. 2013;34(6):974-9. [DOI:10.1097/mao.0b013e31828d676d]
[20] Mangabeira Albernaz PL, Zuma e Maia FC. The video head impulse test. Acta Otolaryngol. 2014;134(12):1245-50. [DOI:10.3109/00016489.2014.942439]
[21] Judge PD, Rodriguez AI, Barin K, Janky KL. Impact of target distance, target size, and visual acuity on the video head impulse test. Otolaryngol Head Neck Surg. 2018;159(4):739-42. [DOI:10.1177%2F0194599818779908]
[22] Ertugrul O, Mutlu A, Zindanci I, Cam OH, Ozluoglu L. Audiological and vestibular measurements in Behçet’s disease. Eur Arch Otorhinolaryngol. 2019;276(6):1625-32. [DOI:10.1007/s00405-019-05403-x]
[23] Tutar B, Berkiten G, Karaketir S, Akan O, Tuna ÖB, Uyar Y. Evaluation of the effect of Behçet’s disease on vestibulo-ocular reflex with video head impulse test. Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi. 2020;28(2):110-6. [DOI:10.24179/kbbbbc.2019-73123]
[24] Curthoys IS, MacDougall HG, McGarvie LA, Weber KP, Szmulewicz D, Manzari L, et al. The Video Head Impulse Test (vHIT). In: Jacobson GP, Shepard NT, editors. Balance Function Assessment and Management. 2th ed. San Diego, CA: Plural Publishing; 2016. p. 391-424.
[25] Jafarzadeh S, Bahrami E, Pourbakht A, Jalaie S, Daneshi A. Validity and reliability of the Persian version of the dizziness handicap inventory. J Res Med Sci. 2014;19(8):769-75.
[26] Gemignani G, Berrettini S, Bruschini P, Sellari-Franceschini S, Fusari P, Piragine F, et al. Hearing and vestibular disturbances in Behçet’s syndrome. Ann Otol Rhinol Laryngol. 1991;100(6):459-63. [DOI:10.1177/000348949110000606]
[27] Belkahia A, Ben Ayed H, Ben H’Mida M, Hamza A. [Auditory and vestibular lesions in Behcet’s disease]. Ann Otolaryngol Chir Cervicofac. 1982;99(10-11):469-76. French.
[28] Brama I, Fainaru M. Inner ear involvement in Behçet’s disease. Arch Otolaryngol. 1980;106(4):215-7. [DOI:10.1001/archotol.1980.00790280023004]
[29] Kulahli I, Balci K, Koseoglu E, Yuce I, Cagli S, Senturk M. Audio-vestibular disturbances in Behcet’s patients: Report of 62 cases. Hear Res. 2005;203(1-2):28-31. [DOI:10.1016/j.heares.2004.11.020]
[2] Bayir O, Comoglu SS, Ozdek A, Aytac E, Guven H, Ozdal MP, Korkmaz H. Vestibular evoked myogenic potential responses in Behçet’s disease. J Int Adv Otol. 2012;8(1):113-7.
[3] Pollak L, Luxon LM, Haskard DO. Labyrinthine involvement in Behçet’s syndrome. J Laryngol Otol. 2001;115(7):522-9. [DOI:10.1258/0022215011908315]
[4] Marshall SE. Behçet’s disease. Best Pract Res Clin Rheumatol. 2004;18(3):291-311. [DOI:10.1016/j.berh.2004.02.008]
[5] Yazici H, Fresko I, Yurdakul S. Behçet’s syndrome: disease manifestations, management, and advances in treatment. Nat Clin Pract Rheumatol. 2007;3(3):148-55. [DOI:10.1038/ncprheum0436]
[6] Erbek S, Erbek SS, Yilmaz S, Yucel E, Ozluoglu LN. Vestibular evoked myogenic potentials in Behcet’s disease. Eur Arch Otorhinolaryngol. 2008;265(11):1315-20. [DOI:10.1007/s00405-008-0650-8]
[7] Yilmaz S, Simsek I, Cinar M, Erdem H, Kose O, Yazici Y, et al. Patient-driven assessment of disease activity in Behçet’s syndrome: Cross-cultural adaptation, reliability and validity of the Turkish version of the Behçet’s Syndrome Activity Score. Clin Exp Rheumatol. 2013;31(3 Suppl 77):S-77-83.
[8] Girasoli L, Cazzador D, Padoan R, Nardello E, Felicetti M, Zanoletti E, et al. Update on vertigo in autoimmune disorders, from diagnosis to treatment. J Immunol Res. 2018;2018:5072582. [DOI:10.1155/2018/5072582]
[9] Davatchi F, Jamshidi AR, Tehrani Banihashemi A, Gholami J, Forouzanfar MH, Moradi M, et al. Prevalence of Behcet’s disease in Iran: a WHO‐ILAR COPCORD stage I study. APLAR J Rheumatol. 2007;10(3):239-43. [DOI:10.1111/j.1479-8077.2007.00295.x]
[10] Davatchi F, Shahram F, Chams‐Davatchi C, Shams H, Nadji A, Akhlaghi M, et al. Behcet’s disease in Iran: Analysis of 6500 cases. Int J Rheum Dis. 2010;13(4):367-73. [DOI:10.1111/j.1756-185X.2010.01549.x]
[11] Shahram F, Nadji A, Jamshidi AR, Chams H, Chams C, Shafaie N, et al. Behcets disease in Iran, analysis of 5,059 cases. Arch Iran Med. 2004;7(1):9-14.
[12] Herdman SJ, Clendaniel R. Vestibular rehabilitation. Philadelphia: F. A. Davis Company; 2014.
[13] Kose E, Kamisli S, Dogan M, Tasolar S, Kahraman A, Oztanir MN, et al. The evaluation of vertebrobasilar artery system in neuro‐Behçet and Behçet disease using magnetic resonance angiography. Anat Rec. 2014;297(7):1302-5. [DOI:10.1002/ar.22922 ]
[14] Bayram A, Doğan M, Koç A, Kalkan M, Akçadağ A, Özcan İ. Cervical and ocular vestibular evoked myogenic potentials in Behcet’s disease. Am J Otolaryngol. 2015;36(4):503-8. [DOI:10.1016/j.amjoto.2015.03.004 ]
[15] Evereklioglu C, Cokkeser Y, Doganay S, Er H, Kizilay A. Audio-vestibular evaluation in patients with Behçet’s syndrome. J Laryngol Otol. 2001;115(9):704-8. [DOI:10.1258/0022215011908946]
[16] McCaslin DL, Jacobson GP. Vestibular-Evoked Myogenic Potentials (VEMPs). In: Jacobson GP, Shepard NT, editors. Balance Function Assessment and Management. 2nd ed. San Diego, CA: Plural Publishing; 2016. p. 533-79.
[17] Wuyts FL, Furman J, Vanspauwen R, Van de Heyning P. Vestibular function testing. Curr Opin Neurol. 2007;20(1):19-24. [DOI:10.1097/WCO.0b013e3280140808]
[18] Abdel Baki NM, Zahran AMA, Dabbous AO, Koura RA, Hamdy MM. Cervical vestibular evoked myogenic potential and high-frequency audiometry results in Behçet’s disease. Egypt Rheumatol Rehabil. 2021;48:3. [DOI:10.1186/s43166-020-00052-z]
[19] MacDougall HG, McGarvie LA, Halmagyi GM, Curthoys IS, Weber KP. Application of the video head impulse test to detect vertical semicircular canal dysfunction. Otol Neurotol. 2013;34(6):974-9. [DOI:10.1097/mao.0b013e31828d676d]
[20] Mangabeira Albernaz PL, Zuma e Maia FC. The video head impulse test. Acta Otolaryngol. 2014;134(12):1245-50. [DOI:10.3109/00016489.2014.942439]
[21] Judge PD, Rodriguez AI, Barin K, Janky KL. Impact of target distance, target size, and visual acuity on the video head impulse test. Otolaryngol Head Neck Surg. 2018;159(4):739-42. [DOI:10.1177%2F0194599818779908]
[22] Ertugrul O, Mutlu A, Zindanci I, Cam OH, Ozluoglu L. Audiological and vestibular measurements in Behçet’s disease. Eur Arch Otorhinolaryngol. 2019;276(6):1625-32. [DOI:10.1007/s00405-019-05403-x]
[23] Tutar B, Berkiten G, Karaketir S, Akan O, Tuna ÖB, Uyar Y. Evaluation of the effect of Behçet’s disease on vestibulo-ocular reflex with video head impulse test. Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi. 2020;28(2):110-6. [DOI:10.24179/kbbbbc.2019-73123]
[24] Curthoys IS, MacDougall HG, McGarvie LA, Weber KP, Szmulewicz D, Manzari L, et al. The Video Head Impulse Test (vHIT). In: Jacobson GP, Shepard NT, editors. Balance Function Assessment and Management. 2th ed. San Diego, CA: Plural Publishing; 2016. p. 391-424.
[25] Jafarzadeh S, Bahrami E, Pourbakht A, Jalaie S, Daneshi A. Validity and reliability of the Persian version of the dizziness handicap inventory. J Res Med Sci. 2014;19(8):769-75.
[26] Gemignani G, Berrettini S, Bruschini P, Sellari-Franceschini S, Fusari P, Piragine F, et al. Hearing and vestibular disturbances in Behçet’s syndrome. Ann Otol Rhinol Laryngol. 1991;100(6):459-63. [DOI:10.1177/000348949110000606]
[27] Belkahia A, Ben Ayed H, Ben H’Mida M, Hamza A. [Auditory and vestibular lesions in Behcet’s disease]. Ann Otolaryngol Chir Cervicofac. 1982;99(10-11):469-76. French.
[28] Brama I, Fainaru M. Inner ear involvement in Behçet’s disease. Arch Otolaryngol. 1980;106(4):215-7. [DOI:10.1001/archotol.1980.00790280023004]
[29] Kulahli I, Balci K, Koseoglu E, Yuce I, Cagli S, Senturk M. Audio-vestibular disturbances in Behcet’s patients: Report of 62 cases. Hear Res. 2005;203(1-2):28-31. [DOI:10.1016/j.heares.2004.11.020]
| Files | ||
| Issue | Vol 31 No 4 (2022) | |
| Section | Research Article(s) | |
| DOI | https://doi.org/10.18502/avr.v31i4.10729 | |
| Keywords | ||
| Cervical vestibular evoked myogenic potentials video head impulse test saccule semicircular canals behcet’s disease | ||
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How to Cite
1.
Heidari Sharifabad Z, Hajiabolhassan F, Hoseinabadi R, Faezi ST, Jalaie S. Assessment of Saccular and Semicircular Canal’s Function in Behcet’s Disease. Aud Vestib Res. 2022;31(4):249-263.
