Tehran University of Medical Sciences Auditory and Vestibular Research 2423-480X 0 0 2025 10 14 1476 1476 EN Nasrin Gohari Department of AudiologyUniversity of Social Welfare and Rehabilitation Sciences.Tehran.Iran Sepideh Ghasemi . Department of Audiology, School of Rehabilitation, Hamadan University of Medical Sciences, Hamadan, Iran Mahdi Khoshfetrat Department of Audiology, School of Rehabilitation, Hamadan University of Medical Sciences, Hamadan, Iran 2025 07 19 2025 09 09 Background and Aim: Hormones have various effects on different parts of the body, and their role in the auditory system has also been confirmed. The aim of this study was to provide a comprehensive review of various studies that have been conducted on the effects of various hormones on the auditory system. Recent Findings : Various hormones, including estrogen, progesterone, prolactin, oxytocin, aldosterone, growth hormone, dopamine, thyroxine (T4), triiodothyronine (T3), parathyroid hormone, cortisol, norepinephrine, insulin, and melatonin  play different roles in the body, including influencing the auditory system. The protective effect of estrogen, aldosterone, norepinephrine, melatonin, and oxytocin against noise, the positive effect of growth hormone on the development of hair cells, sensorineural hearing loss caused by high or low levels of thyroid hormones, low levels of parathyroid hormone, low levels of insulin, low levels of melatonin, and low levels of dopamine, tinnitus and hyperacusis in high levels of cortisol, and early-onset presbycusis in women due to the presence of prolactin. Conclusion: This study showed that hormones play an important role in the function of the auditory system and can affect the development and maturation of auditory structures and their function. Any disruption in hormonal balance may lead to temporary or permanent changes in the auditory system. https://avr.tums.ac.ir/index.php/avr/article/view/1476